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- DOI 10.18231/j.ijceo.v.11.i.3.29
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Ocular tuberculosis manifestation patients attending a tertiary care center
The objective is to determine the incidence of ocular manifestation of tuberculosis in a tertiary care center and to study different clinical manifestations of ocular tuberculosis for early and specific diagnosis. Ocular tuberculosis (TB) is an infection caused by M. tuberculosis (MTB) involving eye, with or without systemic manifestation. Tuberculosis of eye represents a challenging task for a clinician in diagnosis and treatment. This study is a small step to explore various clinical manifestation of ocular tuberculosis. The present study represents prospective observational study conducted from 2018 to 2023 at a tertiary center focusing on the various clinical manifestation and diagnosis of ocular tuberculosis.
The present study consists of 11 ocular tuberculosis cases 9 cases having bilateral ocular involvement. The most common clinical presentation is retinal vasculitis (45%) followed by intermediate uveitis (9%), multifocal choroiditis, (9%). For ophthalmologists it is imperative to know different morphological presentations of ocular tuberculosis. The Ocular Tuberculosis is diagnosed based on the high index of suspicion, typical clinical manifestations supported by modern molecular microbiological assays and a therapeutic response to Anti tubercular treatment.
References
- Grodsky JD, Lee J, Piri N. Presumed ocular tuberculosis: a retrospective case review. J Ophthalmol Res. 2022;5:108–16.
- Kumar A, Chawl R, Sharma N. Ocular tuberculosis. In: Essentials in Ophthalmology. Cham, Switzerland: Springer International Publishing AG; 2017.
- Nussenblatt RB. The natural history of uveitis. Int Ophthalmol. 1990;14(5-6):303–8.
- Testi I, Agrawal R, Mahajan S, Agarwal A, Gunasekeran DV, Raje D, et al. Tubercular uveitis: nuggets from collaborative ocular tuberculosis study (COTS)-1. Ocul Immunol Inflamm. 2020;28(sup1):8–16.
- Agrawal R, Agarwal A, Jabs DA, Kee A, Testi I, Mahajan S, et al. Standardization of nomenclature for ocular tuberculosis - results of Collaborative Ocular Tuberculosis Study (COTS) Workshop. Ocul Immunol Inflamm. 2020;28(sup1):74–84.
- Gunasekeran DV, Agrawal R, Agarwal A, Carreño E, Raje D, Aggarwal K, et al. The Collaborative Ocular Tuberculosis Study (COTS)-1: a multinational review of 251 patients with tubercular retinal vasculitis. Retina. 2019;39(8):1623–30.
- Murphy J, Etti M, Duret A, Papineni P. Ocular tuberculosis: a case series from a London hospital. Int J Infect Dis. 2021;101(S1):452–
- Agarwal A, Agrawal R, Gunasekaran DV, Raje D, Gupta B, Aggarwal K, et al. The Collaborative Ocular Tuberculosis Study (COTS)-1 Report 3: polymerase chain reaction in the diagnosis and management of tubercular uveitis: global trends. Ocul Immunol Inflamm. 2019;27(3):465–73. 550 Rathnaiah / Indian Journal of Clinical and Experimental Ophthalmology 2025;11(3):545–550
- Tsui J, Poon SHL, Fung NSK. Ocular manifestations and diagnosis of tuberculosis involving the uvea: a case series. Trop Dis Travel Med Vaccines. 2023;9(1):20.
- Sudheer B, Lalitha P, Kumar AL, Rathinam S. Polymerase chain reaction and its correlation with clinical features and treatment response in tubercular uveitis. Ocul Immunol Inflamm. 2018;26(6):845–52.
- Lee C, Agrawal R, Pavesio C. Ocular tuberculosis--a clinical conundrum. Ocul Immunol Inflamm. 2016;24(2):237–42.
- Agrawal R, Gunasekeran DV, Raje D, Agarwal A, Nguyen QD, Kon OM, et al. Global variations and challenges with tubercular uveitis in the Collaborative Ocular Tuberculosis Study. Invest Ophthalmol Vis Sci. 2018;59(10):4162–71.
- Agarwal A, Aggarwal K, Gupta V. Infectious uveitis: an Asian perspective. Eye (Lond). 2019;33(1):50–65.
- Abd ZA. Tuberculosis of the eye, case series study. J Med Life. 2022;15(8):1058–62
- Teixeira-Lopes F, Alfarroba S, Dinis A, Gomes MC, Tavares A. Ocular tuberculosis - a closer look to an increasing reality. Pulmonology. 2018;24(5):289–93.
How to Cite This Article
Vancouver
Rathnaiah R. Ocular tuberculosis manifestation patients attending a tertiary care center [Internet]. Indian J Clin Exp Ophthalmol. 2025 [cited 2025 Oct 02];11(3):545-550. Available from: https://doi.org/10.18231/j.ijceo.v.11.i.3.29
APA
Rathnaiah, R. (2025). Ocular tuberculosis manifestation patients attending a tertiary care center. Indian J Clin Exp Ophthalmol, 11(3), 545-550. https://doi.org/10.18231/j.ijceo.v.11.i.3.29
MLA
Rathnaiah, Rekha. "Ocular tuberculosis manifestation patients attending a tertiary care center." Indian J Clin Exp Ophthalmol, vol. 11, no. 3, 2025, pp. 545-550. https://doi.org/10.18231/j.ijceo.v.11.i.3.29
Chicago
Rathnaiah, R.. "Ocular tuberculosis manifestation patients attending a tertiary care center." Indian J Clin Exp Ophthalmol 11, no. 3 (2025): 545-550. https://doi.org/10.18231/j.ijceo.v.11.i.3.29