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- DOI 10.18231/j.ijceo.v.11.i.3.31
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CrossMark
Clinicopathological case series on ocular surface squamous neoplasia (OSSN) in a rural tertiary care centre
- Author Details:
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Reena Sharma
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Deepti Joshi
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Neha Yadav
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Vandana Yadav *
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Savita Agarwal
Vandana Yadav *
Ocular surface squamous neoplasia (OSSN) is a common malignancy globally, which affects the conjunctiva. It has a varied clinical spectrum and thus presents diagnostic and therapeutic challenges. This case series evaluates the clinical presentation, risk factors, diagnostic strategies, and management outcomes of OSSN. Four cases of histologically confirmed OSSN managed at a tertiary care hospital in North India (UPUMS, Saifai, Etawah) were taken. Data on patient demographics, clinical features, diagnostic techniques, treatment modalities, and follow-up outcomes were collected and analysed. Patients ranged from 40–70 years, with key risk factors including UV exposure. Clinical presentations varied from localised to diffuse conjunctival lesions. Treatment included topical chemotherapy and surgical excision. They were followed for a mean duration of 30.75 months without any recurrence. This case series highlights that OSSN can have a wide variety of clinical presentations and can sometimes mimic pterygium. Impression cytology is used to confirm the diagnosis (it reveals mild, moderate, or severe dysplasia of squamous cells). Treatment requires a tailored approach, including chemotherapy and the ‘no-touch technique’ of surgical excision, to manage neoplasia while preserving the patient’s vision and eye function as much as possible. Regular follow-up is needed to improve outcomes and decrease recurrence rates.
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