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- DOI 10.18231/j.ijceo.v.11.i.3.16
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A cross-sectional study to assess the effect of tear substitutes on keratometric measurements in cataract patients with and without dry eyes
Background: In an era of premium IOLs and increase in patients’ visual demands after cataract surgery, it is important to ensure accurate IOL power calculation. The rising incidence of dry eyes poses a challenge to record accurate keratometric readings required for IOL power calculation. This study was conducted to assess the effect of tear substitutes on keratometry at different time intervals in cataract patients with and without dry eyes.
Materials and Methods: This cross-sectional study was conducted in 260 patients diagnosed to have cataract. They were classified into 2 groups based on TBUT test- 1) Dry eyes 2) Non-dry eyes. Baseline keratometry was performed using optical biometer. Keratometric readings were again obtained at 30 seconds and 5 minutes after instillation of 1 drop of 0.1% Hydroxypropyl methylcellulose. IOL power was calculated with SRK-T formula using keratometric readings at different time intervals. Data was analysed using SPSS software.
Results: At 30 seconds post instillation, in patients with dry eyes, a statistically significant change in keratometry and a subsequent change in IOL power was observed (P < .001), but in patients without dry eyes, this change was not statistically significant (P=0.454 and P=0.47 respectively). There was no statistically significant difference in keratometry and IOL power at 5 minutes in both the groups. Variability of keratometry was observed to be higher in the dry eyes group as compared to the non-dry eyes group.
Conclusion: Instillation of tear substitutes is likely to affect keratometry readings. In cases where they have to be invariably used to stabilize the tear film, keratometry should be done at least 5 minutes after instillation of tear substitutes.
References
- Sahin A, Hamrah P. Clinically relevant biometry. Curr Opin Ophthalmol. 2012;23(1):47–53.
- Chen YA, Hirnschall N, Findl O. Evaluation of 2 new optical biometry devices and comparison with the current gold standard biometer. J Cataract Refract Surg. 2011;37(3):513–7.
- Holladay JT. Standardizing constants for ultrasonic biometry, keratometry, and intraocular lens power calculations. J Cataract Refract Surg. 1997;23(9):1356–70
- Wróbel-Dudzińska D, Osial N, Stępień PW, Gorecka A, Żarnowski T. Prevalence of dry eye symptoms and associated risk factors among university students in Poland. Int J Environ Res Public Health. 2023;20(2):1313.
- Trailokya A, Shirsat A, Wankhede S. Prevailing practices for the management of dry eye disease in India: A questionnaire based survey 2023. Indian J Clin Exp Ophthalmol. 2023;9(4):532–41
- Taneja M. Commentary: Effect of dry eyes on the corneal diagnostic measurements. Indian J Ophthalmol. 2022:70(4):1157–8.
- Nibandhe AS, Donthineni PR. Understanding and optimizing ocular biometry for cataract surgery in dry eye disease: A review. Semin Ophthalmol. 2023;38(1):24–30.
- Arif FAC, Hilmi MR, Kamal K, Ithnin MH. Evaluation of 18 artificial tears based on viscosity and pH. Malays J Ophthalmol. 2020;2(2):96–111.
- Nilsen C, Gundersen M, Jensen PG, Gundersen KG, Potvin R, Utheim ØA, et al. The significance of dry eye signs on preoperative keratometry measurements in patients scheduled for cataract surgery. Clin Ophthalmol. 2024;18:151–61.
- Pauk SV, Petriček I, Jukić T, Popović-Suić S, Tomić M, Kalauz M, et al. Noninvasive tear film break-up time assessment using handheld lipid layer examination instrument. Acta Clin Croat. 2019;58(1):63–71.
- Röggla V, Leydolt C, Schartmüller D, Schwarzenbacher L, Meyer E, Abela-Formanek C, et al. Influence of artificial tears on keratometric measurements in cataract patients. Am J Ophthalmol. 2021;221:1–8.
- Teshigawara T, Meguro A, Mizuki N. Effects of rebamipide on differences in power and axis of corneal astigmatism between two intra-patient keratometric measurements in dry eyes. Ophthalmol Ther. 2021;10(4):891–904.
- Montés-Micó R, Cáliz A, Alió JL. Changes in ocular aberrations after instillation of artificial tears in dry-eye patients. J Cataract Refract Surg. 2004;30(8):1649–52.
- Hiraoka T, Asano H, Ogami T, Nakano S, Okamoto Y, Yamada Y, et al. Influence of dry eye disease on the measurement repeatability of corneal curvature radius and axial length in patients with cataract. J Clin Med. 2022;11(3):710.
- Jensen MN, Søndergaard AP, Pommerencke C, Møller F. Variations in keratometric values (K-value) after administration of three different eye drops - effects on the intraocular lens calculations in relation to cataract surgery. Acta Ophthalmol. 2020;98(6):613–7.
How to Cite This Article
Vancouver
Mahale AU, Muzumdar DV, Kulkarni VN, Pandhre JB, Agrawal S, Gadewar SM, Survase BB. A cross-sectional study to assess the effect of tear substitutes on keratometric measurements in cataract patients with and without dry eyes [Internet]. Indian J Clin Exp Ophthalmol. 2025 [cited 2025 Oct 02];11(3):460-465. Available from: https://doi.org/10.18231/j.ijceo.v.11.i.3.16
APA
Mahale, A. U., Muzumdar, D. V., Kulkarni, V. N., Pandhre, J. B., Agrawal, S., Gadewar, S. M., Survase, B. B. (2025). A cross-sectional study to assess the effect of tear substitutes on keratometric measurements in cataract patients with and without dry eyes. Indian J Clin Exp Ophthalmol, 11(3), 460-465. https://doi.org/10.18231/j.ijceo.v.11.i.3.16
MLA
Mahale, Amogha Uday, Muzumdar, Deepa Vishwesh, Kulkarni, Varsha Nitin, Pandhre, Jayshri Baswaraj, Agrawal, Sanjiv, Gadewar, Shivali Madhusudan, Survase, Bhavana Bhanudas. "A cross-sectional study to assess the effect of tear substitutes on keratometric measurements in cataract patients with and without dry eyes." Indian J Clin Exp Ophthalmol, vol. 11, no. 3, 2025, pp. 460-465. https://doi.org/10.18231/j.ijceo.v.11.i.3.16
Chicago
Mahale, A. U., Muzumdar, D. V., Kulkarni, V. N., Pandhre, J. B., Agrawal, S., Gadewar, S. M., Survase, B. B.. "A cross-sectional study to assess the effect of tear substitutes on keratometric measurements in cataract patients with and without dry eyes." Indian J Clin Exp Ophthalmol 11, no. 3 (2025): 460-465. https://doi.org/10.18231/j.ijceo.v.11.i.3.16