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- DOI 10.18231/j.ijceo.v.11.i.3.15
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CrossMark
- Citation
Diabetic retinopathy among newly diagnosed diabetics
- Author Details:
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Avin M Khushiramani *
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Yogendra G Vabale
Background: Diabetes is a major metabolic disorder affecting diverse populations. Approximately 415 million people worldwide have diabetes, a number expected to increase by 200% by 2030. Diabetic retinopathy (DR) is a leading cause of preventable blindness.
Aim and Objective: To estimate the prevalence and associated risk factors of diabetic retinopathy among newly diagnosed diabetic patients.
Materials and Methods: A cross-sectional observational study at the Ophthalmology Department at MIMER Medical College, Pune, Maharashtra, India. After obtaining Institutional Ethical Committee approval, 138 newly diagnosed diabetic patients visiting the Ophthalmology OPD were selected using purposive sampling. After obtaining informed consent patients underwent comprehensive ophthalmological evaluations and were classified using the Early Treatment Diabetic Retinopathy Study (ETDRS) system. The data was analysed using SPSS software version 21 and represented in form of frequency and percentages. Statistical analysis was applied and p-value <0.05 was considered significant.
Results: The mean age of the 138 subjects was 55.61 ± 9.16 years. Diabetic retinopathy was observed in 15 (10.9%) of subjects. Mild, moderate, and severe non-proliferative DR prevalence was 4.3%, 3.6%, and 2.2%, respectively, while proliferative DR was present in 0.8% of subjects. Logistic regression identified HbA1c levels as significant predictors of DR.
Conclusions: Age and HbA1c levels are significant predictors of DR, highlighting the need for early screening and intervention in diabetic patients to prevent vision loss.
References
- International Diabetes Federation. IDF Diabetes Atlas, 7th Edition [cited 2024 September]. Available from: http://www.diabetesatlas.org/.
- Pradeepa R, Mohan V. Epidemiology of type 2 diabetes in India. Indian J Ophthalmol. 2021;69(11):2932–8.
- Pradeepa R, Mohan V. Prevalence of type 2 diabetes and its complications in India and economic costs to the nation. Eur J Clin Nutr. 2017;71(7):81624.
- Fong DS, Aiello L, Gardner TW, King GL, Blankenship G, Cavallerano JD, et al. Diabetic Retinopathy. Diabetes Care. 2003;26(Suppl 1):s99–s102.
- Farmer A. Monitoring diabetes. In: Holt RIG, Cockram CS, Flyvbjerg Goldstein BJ, editors. Textbook of Diabetes. 5th ed. USA: Wiley Blackwell; 2017. p. 374–84.
- Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med. 1993;329(14):977–86.
- Stratton IM, Adler AI, Neil HA, Matthews DR, Manley SE, Cull CA, et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ. 2000;321(7258):405–12.
- Wang W, Lo ACY. Diabetic Retinopathy: Pathophysiology and Treatments. Int J Mol Sci. 2018;19(6):1816.
- Shukla UV, Tripathy K. Diabetic Retinopathy. [Updated 2023 Aug 25]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan . Available from: https://www.ncbi.nlm.nih.gov/books/NBK560805/
- Wong TY, Sun J, Kawasaki R, Ruamviboonsuk P, Gupta N, Lansingh VC, et al. Guidelines on diabetic eye care: The International Council of Ophthalmology recommendations for screening, follow-up, referral, and treatment based on resource settings. Ophthalmology. 2018;125(10):1608–22.
- Nentwich MM, Ulbig MW. Diabetic retinopathy - ocular complications of diabetes mellitus. World J Diabetes. 2015;6(3):489–99.
- Crabtree GS, Chang JS. Management of complications and vision loss from proliferative diabetic retinopathy. Curr Diab Rep. 2021;21(9):33.
- Lima VC, Cavalieri GC, Lima MC, Nazario NO, Lima GC. Risk factors for diabetic retinopathy: a case-control study. Int J Retina Vitreous. 2016;2:21.
- Al-Rubeaan K, Abu El-Asrar AM, Youssef AM, Subhani SN, Ahmad NA, Al-Sharqawi AH, et al. Diabetic retinopathy and its risk factors in a society with a type 2 diabetes epidemic: a Saudi National Diabetes Registry-based study. Acta Ophthalmol. 2015;93(2):e140–
- Agarwal M, Rani PK, Raman R, Narayanan R, Sreenivasamurthy L, Virmani A, et al. Diabetic retinopathy screening guidelines for physicians in India: position statement by the Research Society for the Study of Diabetes in India (RSSDI) and the Vitreoretinal Society of India (VRSI)-2023. Int J Diabetes Dev Ctries. 2024;44:32–9.
- Mathur P, Leburu S, Kulothungan V. Prevalence, awareness, treatment and control of diabetes in India from the countrywide national NCD monitoring survey. Front Public Health. 2022;10:748157.
- Bernardes R, Serranho P, Lobo C. Digital ocular fundus imaging: A review. Ophthalmologica. 2011;226(4):161–81.
- Hee MR, Puliafito CA, Duker JS, Reichel E, Coker JG, Wilkins JR, et al. Topography of diabetic macular edema with optical coherence tomography. Ophthalmology. 1998;105(2):360–70.
- Silva PS, Liu D, Glassman AR, Aiello LP, Grover S, Kingsley RM, et al. DRCR Retina Network. Assessment of fluorescein angiography nonperfusion in eyes with diabetic retinopathy using ultrawide field retinal imaging. Retina. 2022;42(7):1302–10.
- Sharon D. Solomon, Morton F. Goldberg; ETDRS Grading of Diabetic Retinopathy: Still the gold standard?. Ophthalmic Res. 2019;62 (4):190–5.
- Rema M, Deepa R, Mohan V. Prevalence of retinopathy at diagnosis among type 2 diabetic patients attending a diabetic centre in south India. Br J Ophthalmol. 2000;84(9):1058–60.
- Abdollahi A, Malekmadani M, Mansoori M, Bostak A, Abbaszadeh M, Mirshahi A. Prevalence of diabetic retinopathy in patients with newly diagnosed type II diabetes mellitus. Acta Med Iran. 2006;44(6):415–9.
- Hamid A, Golar SK, Wharton HM, Clarke M, Wright A. Diabetic retinopathy in newly diagnosed diabetes after kidney and liver transplantation. Br J Diabetes. 2017;17(1):17–8.
- Hao Z, Huang X, Qin Y, Li H, Tian F, Xu R, et al. Analysis of factors related to diabetic retinopathy in patients with newly diagnosed type 2 diabetes: a cross-sectional study. BMJ Open. 2020;10(2):e032095.
- Shah S, Feher M, McGovern A, Sherlock J, Whyte MB, Munro N, et al. Diabetic retinopathy in newly diagnosed Type 2 diabetes mellitus: prevalence and predictors of progression; a national primary network study. Diabetes Res Clin Pract. 2021;175:108776.
- Damor DV, Bhojak DA, Mahant DA, Mahaliya DN. To evaluate the incidence of diabetic retinopathy in newly diagnosed diabetic patients presented at tertiary care hospital: Diabetic retinopathy in newly diagnosed diabetic patients. Natl J Integr Res Med. 2022;13(2):62–6.
- Chowdhury SR, Thomas RL, Dunseath GJ, Luzio SD, Wong FS, Owens DR. Incidence of diabetic retinopathy in newly diagnosed subjects with type 2 diabetes mellitus over 5 years: contribution of Β-cell function. J Diabetes Complications. 2022;36(1):108028.
- Khan WJ, Aslam T. Frequency of retinopathy in patients newly diagnosed with Type 2 diabetes mellitus. Cureus. 2023;15(3):e36513.
- Setia S, Tidake P. Prevalence and awareness of diabetic retinopathy in diabetic patients visiting tertiary care hospitals in central India. Cureus. 2023;15(5):e39414. Khushiramani and Vabale / Indian Journal of Clinical and Experimental Ophthalmology 2025;11(3):454–459 459
- Sofizadeh S, Eeg-Olofsson K, Lind M. Prevalence and risk factors for diabetic retinopathy at diagnosis of type 2 diabetes: an observational study of 77 681 patients from the Swedish National Diabetes Registry. BMJ Open Diabetes Res Care . 2024;12(3):e003976.
- Chung YC, Xu T, Tung TH, Chen M, Chen PE. Early screening for diabetic retinopathy in newly diagnosed Type 2 diabetes and its effectiveness in terms of morbidity and clinical treatment: a nationwide population-based cohort. Front Public Health. 2022;10:771862.
- Cai K, Liu YP, Wang D. Prevalence of diabetic retinopathy in patients with newly diagnosed type 2 diabetes: A systematic review and meta-analysis. Diabetes Metab Res Rev. 2023;39(1):e3586.
How to Cite This Article
Vancouver
Khushiramani AM, Vabale YG. Diabetic retinopathy among newly diagnosed diabetics [Internet]. Indian J Clin Exp Ophthalmol. 2025 [cited 2025 Oct 23];11(3):454-459. Available from: https://doi.org/10.18231/j.ijceo.v.11.i.3.15
APA
Khushiramani, A. M., Vabale, Y. G. (2025). Diabetic retinopathy among newly diagnosed diabetics. Indian J Clin Exp Ophthalmol, 11(3), 454-459. https://doi.org/10.18231/j.ijceo.v.11.i.3.15
MLA
Khushiramani, Avin M, Vabale, Yogendra G. "Diabetic retinopathy among newly diagnosed diabetics." Indian J Clin Exp Ophthalmol, vol. 11, no. 3, 2025, pp. 454-459. https://doi.org/10.18231/j.ijceo.v.11.i.3.15
Chicago
Khushiramani, A. M., Vabale, Y. G.. "Diabetic retinopathy among newly diagnosed diabetics." Indian J Clin Exp Ophthalmol 11, no. 3 (2025): 454-459. https://doi.org/10.18231/j.ijceo.v.11.i.3.15