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- DOI 10.18231/j.ijceo.v.11.i.3.12
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CrossMark
Unveiling the impact of refitting with new daily wear silicone hydrogel lenses on dryness and discomfort
- Author Details:
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Ankur Banik *
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Kumari Priyanka
Ankur Banik *
Background: Contact lens wear offers convenient vision correction, but dryness and discomfort remain common, affecting ocular health and quality of life. This study aims to assess dryness and discomfort in symptomatic silicone hydrogel lens wearers and evaluate symptom improvement following refitting with new silicone hydrogel lenses.
Materials and Methods: Symptomatic participants attended two clinical visits: those wearing habitual contact lenses (Balafilcon A or Lotrafilcon B) during the initial visit and those transitioning to study silicone hydrogel lenses (Samfilcon A) at the first follow-up. Symptoms related to contact lens dryness and discomfort was measured using the Contact lens dry eye questionnaire-8 (CLDEQ-8) during both visits. A thorough examination of the eyes and contact lenses was performed, followed by an assessment of dry eye. Subsequently, all participants were fitted with the study silicone hydrogel lenses and re-evaluated after two-weeks.
Results: Sixty participants completed the trial. Participants reported higher CLDEQ-8 scores while wearing their habitual contact lenses compared to when wearing study silicone hydrogel lenses (12.8 ± 2.6 vs. 3.2 ± 2.9, P <.0001). Upon comparing two visits, significant increases were noted in Schirmer 1 (22.0 ± 3.4 vs. 22.4 ± 2.9, P<.05), Schirmer 2 (19.7 ± 3.2 vs. 20.4 ± 2.9, P<.01) and Tear Breakup Time (TBUT) (7.4 ± 0.9 vs. 10.0 ± 0.8, P<.0001). Notably, moderately negative correlations were observed between CLDEQ-8 and TBUT (r = -0.39 vs. -0.34), Schirmer 1 (r = -0.07 vs. -0.07), and Schirmer 2 (r = -0.17 vs. -0.07) during both visits.
Conclusion: The current study demonstrated that the tear function profile and CLDEQ-8 scores significantly improved after a two-week study lens usage, indicating improved subjective dryness and discomfort.
References
- Chaudhary S, Ghimire D, Basu S, Agrawal V, Jacobs DS, Shanbhag SS. Contact lenses in dry eye disease and associated ocular surface disorders. Indian J Ophthalmol. 2023;71(4):1142–53.
- Jones L, Efron N, Bandamwar K, Barnett M, Jacobs DS, Jalbert I, et al. TFOS lifestyle: impact of contact lenses on the ocular surface. Ocul Surf. 2023;29:175–219.
- McMonnies CW. Could contact lens dryness discomfort symptoms sometimes have a neuropathic basis? Eye Vis (Lond). 2021;8(1):12.
- Kojima T. Contact lens-associated dry eye disease: recent advances worldwide and in Japan. Invest Ophthalmol Vis Sci. 2018;59(14):DES102–8.
- Markoulli M, Kolanu S. Contact lens wear and dry eyes: challenges and solutions. Clin Optom (Auckl). 2017;9:41–8.
- Nichols KK, Redfern RL, Jacob JT, Nelson JD, Fonn D, Forstot SL, et al. The TFOS International Workshop on Contact Lens Discomfort: report of the definition and classification subcommittee. Invest Ophthalmol Vis Sci. 2013;54(11):TFOS14–9.
- Reddy SC, Ying KH, Theng LH, How OT, Fu-Xiang PK, Sikander MM. A survey of dry eye symptoms in contact lens wearers and non- contact lens wearers among university students in Malaysia. J Clin Exp Ophthalmol. 2016;7:511.
- Schafer J, Reindel W, Steffen R, Mosehauer G, Chinn J. Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses. Clin Ophthalmol. 2018;12:819–25.
- Szczesna-Iskander DH. Comparison of tear film surface quality measured in vivo on water gradient silicone hydrogel and hydrogel contact lenses. Eye Contact Lens. 2014;40(1):23–7.
- Ribeiro M, Vieira MS, Gorgone G, Barbosa LYC, Martini ARAF, David MA, et al. The contact lens dry eyes questionnaire (CLDEQ- 8) validation and ocular surface dysfunction among soft contact lens wearers. Arq Bras Oftalmol. 2022;85(1):68–76. 440 Banik and Priyanka / Indian Journal of Clinical and Experimental Ophthalmology 2025;11(3):435–440
- Huntjens B, Basi M, Nagra M. Evaluating a new objective grading software for conjunctival hyperaemia. Cont Lens Anterior Eye. 2020;43(2):137–43.
- Vidas Pauk S, Petriček I, Jukić T, Popović-Suić S, Tomić M, Kalauz M, et al. Noninvasive tear film break-up time assessment using handheld lipid layer examination instrument. Acta Clin Croat. 2019;58(1):63–71.
- Wolffsohn JS, Arita R, Chalmers R, Djalilian A, Dogru M, Dumbleton K, et al. TFOS DEWS II diagnostic methodology report. Ocul Surf. 2017;15(3):539–74.
- Sulley A, Lorenz KO, Wolffsohn JS, Young G. Theoretical fitting characteristics of typical soft contact lens designs. Cont Lens Anterior Eye. 2017;40(4):248–52.
- Pucker AD, Tichenor AA. A review of contact lens dropout. Clin Optom (Auckl). 2020;12:85–94.
- Sulley A, Young G, Hunt C. Factors in the success of new contact lens wearers. Cont Lens Anterior Eye. 2017;40(1):15–24.
- Nichols JJ, Willcox MDP, Bron AJ, Belmonte C, Ciolino JB, Craig JP, et al. The TFOS International Workshop on Contact Lens Discomfort: executive summary. Invest Ophthalmol Vis Sci. 2013;54(11):TFOS7–13.
- Guillon M, Dumbleton KA, Theodoratos P, Wong S, Patel K, Banks G, et al. Association between contact lens discomfort and pre-lens tear film kinetics. Optom Vis Sci. 2016;93(8):881–91.
- Wu Z, Begley CG, Port N, Bradley A, Braun R, King-Smith E. The effects of increasing ocular surface stimulation on blinking and tear secretion. Invest Ophthalmol Vis Sci. 2015;56(8):4211–20.
- King-Smith PE, Begley CG, Braun RJ. Mechanisms, imaging and structure of tear film breakup. Ocul Surf. 2018;16(1):4–30.
- Tsubota K. Short tear film breakup time-type dry eye. Invest Ophthalmol Vis Sci. 2018;59(14):DES64–DES70.
- Kastelan S, Lukenda A, Salopek-Rabatić J, Pavan J, Gotovac M. Dry eye symptoms and signs in long-term contact lens wearers. Coll Antropol. 2013;37(Suppl 1):199–203.
- Craig JP, Willcox MDP, Argüeso P, Maissa C, Stahl U, Tomlinson A, et al. The TFOS International Workshop on Contact Lens Discomfort: report of the contact lens interactions with the tear film subcommittee. Invest Ophthalmol Vis Sci. 2013;54(11):TFOS123–
- Mousavi M, Jesus DA, Garaszczuk IK, Szczesna-Iskander DH, Iskander DR. The utility of measuring tear film break-up time for prescribing contact lenses. Cont Lens Anterior Eye. 2018;41(1):105–9.
- Giannaccare G, Blalock W, Fresina M, Vagge A, Versura P. Intolerant contact lens wearers exhibit ocular surface impairment despite 3 months wear discontinuation. Graefes Arch Clin Exp Ophthalmol. 2016;254(9):1825–31.
- García-Montero M, Rico-Del-Viejo L, Llorens-Quintana C, Lorente-Velázquez A, Hernández-Verdejo JL, Madrid-Costa D. Randomized crossover trial of silicone hydrogel contact lenses. Cont Lens Anterior Eye. 2019;42(5):475–81.
- López-de la Rosa A, Arroyo-Del Arroyo C, Enríquez-de-Salamanca A, Pinto-Fraga J, López-Miguel A, González-García MJ. The ability of the Contact Lens Dry Eye Questionnaire (CLDEQ)-8 to detect ocular surface alterations in contact lens wearers. Cont Lens Anterior Eye. 2019;42(3):273–7.
- Pucker AD, Dougherty BE, Jones-Jordan LA, Kwan JT, Kunnen CME, Srinivasan S. Psychometric analysis of the SPEED questionnaire and CLDEQ-8. Invest Ophthalmol Vis Sci. 2018;59(8):3307–13.
- Sulley A, Dumbleton K. Silicone hydrogel daily disposable benefits: The evidence. Cont Lens Anterior Eye. 2020;43(3):298–307.
- Lin CH, Cho HL, Yeh YH, Yang MC. Improvement of the surface wettability of silicone hydrogel contact lenses via layer-by-layer self-assembly technique. Colloids Surf B Biointerfaces. 2015;136:735–43.
- Omali NB, Subbaraman LN, Heynen M, Ng A, Coles-Brennan C, Fadli Z, et al. Surface versus bulk activity of lysozyme deposited on hydrogel contact lens materials in vitro. Cont Lens Anterior Eye. 2018;41(4):329–34.
- Chan VWY, Phan CM, Ngo W, Jones L. Lysozyme deposition on contact lenses in an in vitro blink-simulation eye model versus a static vial deposition model. Eye Contact Lens. 2021;47(7):388–93.
- Vega J, Orsborn G, Diamanti S. First and third generation silicone hydrogel contact lens physical properties impact on patient preferences. Cont Lens Anterior Eye. 2018;41:S94-S95.
- Hoteling AJ, Nichols WF, Harmon PS, Conlon SM, Nuñez IM, Hoff JW, et al. Characterization and quantitation of PVP content in a silicone hydrogel contact lens produced by dual-phase polymerization processing. J Biomed Mater Res B Appl Biomater. 2018;106(3):1064–72.