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- DOI 10.18231/j.ijceo.v.11.i.3.6
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CrossMark
To study the association of refractive errors, intraocular pressure with systemic blood pressure and BMI in the age group (11-20 years) in comparison with controls of similar age and gender group
- Author Details:
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Aajay Dhanasekharan
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Saswati Sen
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Soumyakanta Mohanty *
Aajay Dhanasekharan
Saswati Sen
Soumyakanta Mohanty *
Background: Refractive errors, eye pressure (IOP), blood pressure, and body weight (BMI) are all closely connected and can affect both vision and overall health—especially during adolescence, a period of rapid growth. With more screen time and less outdoor activity, myopia is on the rise and often linked to higher IOP and BMI, though research shows mixed results. In places like Odisha, where low BMI is common, undernutrition may impact both eye development and systemic health, highlighting the need for region-specific studies.
Aims and Objective: To evaluate the association of refractive errors and intraocular pressure (IOP) with systemic blood pressure (BP) and body mass index (BMI) in adolescents aged 11–20 years, and compare findings with age- and sex-matched emmetropic controls.
Materials and Methods: This comparative cross-sectional study was conducted at a tertiary eye care center in Odisha. A total of 264 participants (134 cases with refractive errors and 130 controls) aged 11–20 years were enrolled. Visual acuity, refraction, IOP, systemic BP, pulse rate, and anthropometric data were collected. Statistical analyses included t-tests, chi-square tests, and two-way ANOVA to assess intergroup differences and associations.
Results: There was no significant difference in age or height between cases and controls. However, cases had significantly higher BMI (p < 0.001), body weight (p = 0.010), and diastolic BP (p = 0.042). Pulse rate was significantly lower in cases (p = 0.004). The prevalence of overweight and obesity was higher among cases, whereas underweight status was more common in controls. IOP was slightly higher in females and positively correlated with BMI and diastolic BP, particularly in myopic individuals. Pulse rate and DBP showed age- and gender-based variations, reinforcing systemic physiological influences on ocular parameters.
Conclusion: Adolescents with refractive errors, particularly myopia, demonstrated higher BMI and Diastolic Blood Pressure (DBP) with lower pulse rates, indicating possible autonomic and vascular dysregulation. These systemic associations highlight the need for integrated screening strategies addressing both ocular and systemic health during adolescence, especially in nutritionally vulnerable populations like those in Odisha.
References
- Akinci A, Cetinkaya E, Aycan Z, Oner O. Relationship between intraocular pressure and obesity in children. J Glaucoma. 2007;16(7):627–30.
- Akova-Budak B, Argun Kıvanç S, Olcaysü OO. Association of birth parameters with refractive status in a sample of Caucasian children aged 4–17 years. J Ophthalmol. 2015:635682.
- Du W, Ding G, Guo X, Abudukeyimu K, Wang Y, Wang L, et al. Associations between anthropometric indicators and refraction in school-age children during the post-COVID-19 era. Front Public Health. 2023;10:1059465.
- Wong TY, Klein R, Klein BEK, Meuer SM, Hubbard LD. Retinal vessel diameters and their associations with age and blood pressure. Invest Ophthalmol Vis Sci. 2003;44(11):4644–50.
- Li M, Xu Q, Yan X, Wang J, Xiang Y. Relationship between autonomic nervous system activity and axial length in children. Med Sci Monit. 2023;29:e939451.
- Bai WL, Kang YT, Li SM, Gan JH, Wei SF, Kang MT, et al. Mean ocular perfusion pressure and its association with refractive status in Chinese children. Transl Vis Sci Technol. 2022;11(10):26.
- He Y, Li S-M, Kang M-T, Liu L-R, Li H, Wei S-F, et al. Association between blood pressure and retinal arteriolar and venular diameters in Chinese early adolescent children, and whether the association has gender difference: a cross-sectional study. BMC Ophthalmol. 2018;18(1):133.
- Ikuno Y, Kawaguchi K, Nouchi T, Yasuno Y. Choroidal thickness in healthy Japanese subjects. Invest Ophthalmol Vis Sci. 2010;51(4):2173–6.
- Yang DY, Guo K, Wang Y, Guo YY, Yang XR, Jing XX, et al. Intraocular pressure and associations in children. The Gobi Desert Children Eye Study. PLoS One. 2014;9(10):e109355.
- Mitchell P, Cheung N, de Haseth K, Taylor B, Rochtchina E, Islam FMA, et al. Blood pressure and retinal arteriolar narrowing in children. Hypertension. 2007;49(5):1156–62.
- Takagi H, Umemoto T. Overweight, but not obesity, paradox on mortality following coronary artery bypass grafting. J Cardiol. 2016;68(3):215–21.
- Anderson LN, Carsley S, Lebovic G, Borkhoff CM, Maguire JL, Parkin PC, et al. Misclassification of child body mass index from cut-points defined by rounded percentiles instead of Z-scores. BMC Res Notes. 2017;10(1):639.
- WHO Expert Consultation. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet. 2004;363(9403):157–63. Dhanasekharan et al. / Indian Journal of Clinical and Experimental Ophthalmology 2025;11(3):398–405 405
- Hubbard RE, Lang IA, Llewellyn DJ, Rockwood K. Frailty, body mass index, and abdominal obesity in older people. J Gerontol A Biol Sci Med Sci. 2010;65(4):377–81.
- Peled A, Nitzan I, Megreli J, Derazne E, Tzur D, Pinhas-Hamiel O, et al. Myopia and BMI: a nationwide study of 1.3 million adolescents. Obesity (Silver Spring). 2022;30(8):1691–8.