Indian Journal of Clinical and Experimental Ophthalmology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2395-1443
Online ISSN: 2395-1451
CODEN : IJCEKF
Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...Original Article
Author Details :
Volume : 4, Issue : 4, Year : 2018
Article Page : 530-534
https://doi.org/10.18231/2395-1451.2018.0119
Abstract
Introduction: MPV and PDW are indicators of subclinical platelet hyperactivity and can be used as predictive factors for development and progression of diabetic retinopathy.
Materials and Methods: This prospective case control study enrolled 150 patients with diabetic retinopathy (DR group) and 150 diabetic patients without retinopathy (control group). Detailed history and ophthalmic examination was done. The DR group was divided into 5 subgroups according to the ETDRS classification of diabetic retinopathy. MPV, PDW, FBS and PPBS values were obtained.
Result: The mean value of MPV in DR group was higher compared to control group (p=0.016). PDW also followed the similar trend with DR group having mean value of 13.71± 1.36 fl and control group having 12.13 ± 1.29 fl (p=0.023). The study also found a trend of increase in severity of diabetic retinopathy with increasing level of MPV and PDW. However a statistically significant association was found only between MPV and stage of diabetic retinopathy (r= 0.214, p= 0.046). A marked increase in MPV and PDW values were found in those with Proliferative diabetic retinopathy (p<0> Conclusion: Platelet indices like MPV can be a cheap and easy to measure tool for monitoring diabetic retinopathy.
Keywords: Mean platelet volume, Platelet distribution width, Diabetic retinopathy, Proliferative diabetic retinopathy.
How to cite : Hegde S S, S.r M, Dharwadkar S, Mohammad Abdul Kayoom N, Shashidhar H. B, Association of mean platelet volume and platelet distribution width with diabetic retinopathy in patients with diabetes mellitus. Indian J Clin Exp Ophthalmol 2018;4(4):530-534
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