Indian Journal of Clinical and Experimental Ophthalmology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2395-1443
Online ISSN: 2395-1451
CODEN : IJCEKF
Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...Original Article
Author Details :
Volume : 4, Issue : 3, Year : 2018
Article Page : 333-338
https://doi.org/10.18231/2395-1451.2018.0075
Abstract
Introduction: Keratoconus is a disorder of progressive corneal steepening, resulting in cone shaped protrusion of cornea, corneal thinning, myopia and astigmatism.
Objectives: To assess the efficacy and safety of corneal collagen cross-linking with Riboflavin in the management of keratoconus.
Materials and Methods: The study was conducted at an eye hospital over a period of 22 months to evaluate utility of corneal collagen cross-linking in treatment of keratoconus. Study group included 10 eyes (6 right and 4 left) of 8 patients (6 males and 2 females) with one year follow-up.
Results: Mean age of study population was 24.25 years (SD=5.97; SE=2.11). The mean logMAR UCVA prior to CXL was 0.85 which improved to 0.57 at 12 months. Mean baseline BCVA was 0.464 logMAR, this improved to 0.170 logMAR at 12 months. At baseline a mean SimK astigmatism was 4.99 (SD= 2.56) and this decrease to 4.72 at 12 months.
Conclusion: Present study showed improved visual acuity (both UCVA and BSCVA), stable topographic parameters, stable visual acuity and stable endothelial cell counts over a period of 12 months follow up, indicating that corneal collagen cross-linking with riboflavin is a safe and effective treatment option for keratoconus.
Keywords: Corneal collagen cross-linking and visual acuity, Keratoconus.
How to cite : Srivastava G, Bhatia H K, Sridhar U, A study to evaluate safety and efficacy of corneal collagen cross-linking with riboflavin in keratoconus patients. Indian J Clin Exp Ophthalmol 2018;4(3):333-338
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