Indian Journal of Clinical and Experimental Ophthalmology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2395-1443
Online ISSN: 2395-1451
CODEN : IJCEKF
Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...Original Article
Author Details :
Volume : 4, Issue : 2, Year : 2018
Article Page : 178-181
https://doi.org/10.18231/2395-1451.2018.0040
Abstract
Aim: The purpose of the study is to find the impact of diabetes mellitus on central thickness and endothelial parameters of cornea when compared with non diabetic patients and in relation to duration of disease and glycaemic control.
Study Design: Prospective, Observational and quantitative study.
Materials and Methods: Study included 125 patients (125 eyes) with diabetes mellitus and 143 controls (143 eyes). Tomey specular non-contact microscope (EM 3000) was used to measure central corneal thickness (CCT), endothelial cell density (ECD), coefficient of variation of cell size (CV) and percentage of hexagonal endothelial cells (6A).
Results: Comparison of age matched controls with diabetics did not show any statistical significance with respect to CCT, ECD and CV. 6A showed some significant change (p value= 0.02) between controls and diabetics. There was no significant correlation with respect to the duration of diabetes and glycaemic control.
Conclusion: Corneal endothelial parameters and thickness did not show any statistical significance between diabetics and controls except hexagonality of endothelial cells which was significant. Moreover there was statistically no difference based on duration of the disease, glycaemic control and presence or absence of retinopathy.
Keywords: Central corneal thickness, Endothelial cell density, Diabetes mellitus.
How to cite : Shankar C, Premnath G, Balaji A, Aila L A, Sruthi G, Study of impact of diabetes mellitus on corneal central thickness and endothelial parameters in Indian eyes. Indian J Clin Exp Ophthalmol 2018;4(2):178-181
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