Print ISSN: 2395-1443
Online ISSN: 2395-1451
CODEN : IJCEKF
Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...Original Article
Author Details :
Volume : 4, Issue : 1, Year : 2018
Article Page : 40-45
https://doi.org/10.18231/2395-1451.2018.0011
Abstract
Introduction: Glaucoma is a chronic progressive optic neuropathy characterized by retinal ganglion cell death and associated visual field loss irrespective of intraocular pressure changes. The exact pathophysiological mechanism is not fully understood. The vascular hypothesis of OAG states that a low blood pressure (BP) relative to IOP can lead to low mean ocular perfusion pressure (MOPP), thus impairing perfusion of the Optic Nerve Head (ONH) with resultant glaucomatous cupping and visual field loss.
Objective: To find out any relationship between systemic hypertension, intraocular tension (IOP) and mean ocular perfusion pressure (MOPP) in primary open angle glaucoma (POAG), normal tension glaucoma and normal population.
Materials and Methods: It was a cross-sectional observational study. A total 125 patients attended in eye OPD at Calcutta National Medical College & Hospital, Kolkata, in one year having primary open angle glaucoma including normal tension glaucoma. Patients were distributed into three groups according to the technique of management. Applanation Tonometry and fundoscopic evaluation (+ 90 D lens) were done for all cases. Single recording of BP was taken. Gonioscopy, Humphrey's central visual fields and pachymetry were done. Data analyzed using standard statistical technique and a probability value (‘p’ value) of < 0.05 was considered as statistically significant.
Results: The average age of the study population was 54.38 ±8.92 years and ranging from 41 to 75 years. The study was male preponderant. The relationship between mean arterial pressure, intraocular pressure and mean ocular perfusion pressure was statistically significant in all subgroups.
Conclusion: There was a moderately strong correlation between MAP and MOPP whereas between MAP and IOP was weakly positive. The relationship between IOP and MOPP was inversely correlated.
Keywords: Ocular perfusion pressure, Open-angle glaucoma, Systemic hypertension.
How to cite : Bhattacharyya S, Sarkar* K C, Gedam A S, A comparative study between systemic hypertension, intraocular tension and ocular perfusion pressure in primary open angle glaucoma, normal tension glaucoma and normal population in a tertiary care centre. Indian J Clin Exp Ophthalmol 2018;4(1):40-45
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