Indian Journal of Clinical and Experimental Ophthalmology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2395-1443
Online ISSN: 2395-1451
CODEN : IJCEKF
Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...Original Article
Author Details :
Volume : 3, Issue : 2, Year : 2017
Article Page : 142-146
Abstract
Aim: To study the association of serum uric acid level with age related macular degeneration, if any.
Materials and Method: In this hospital based, observational, case control study, 100 patients presenting to our out patient department over a period of one year were included. The selected participants were grouped into the ARMD group which included 50 eyes with non neovascular ARMD and neovascular ARMD) and 50 eyes in control group. All participants were undergone complete ophthalmic evaluation along with serum uric acid level determination.
Results: 50 eyes of 50 patients diagnosed as having AMD and 50 eyes of 50 patients do not having AMD who served as a control were included in this study. The mean age was 66 years (49-85years). On an average higher serum uric acid were observed amongst males as compared to females (median: male vs female kruskal Wallace test H=22.5, DF=1, p<0.001).The average serum uric acid level were higher in patients with neovascular AMD (mean=505.00 ± std dev =13.57 mmol/l, n=19), than in the non-neovascular AMD (mean=322.93 ± std dev =26.26mmol/l, n=31),as compared to control group =318.42 ± std dev =76.23 mmol/l,n=50). On comparing the standardized serum uric acid level between neovascular AMD and control group, there was a statistically significant difference was observed. (H=40.734, DF=1, p<0.001).
Conclusion: A statistically significant correlation exists between serum uric acid level and severity of age related macular degeneration. Patients with neovascular age related macular degeneration present with a higher serum uric acid level as compared to patients with non neovascular age related maculae degeneration. Also, males had a significantly higher serum uric acid level as compared to females.
Keywords: Neovascular age related macular degeneration, Non neovascular age related macular degeneration, Serum uric acid level.
How to cite : Patel D, Bhattacharjee H, Dhar S, Misra D, Pawar E, A study to determine association of serum uric acid level with age related macular degeneration. Indian J Clin Exp Ophthalmol 2017;3(2):142-146
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