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Role of cyclosporin 0.1% in perennial vernal keratoconjunctivitis

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Original Article

Author Details : Kshama Dwivedi, Arun Kumar Singh, Vanlalhruaii Hauhner, Mimansaa Agasti

Volume : 2, Issue : 3, Year : 2016

Article Page : 190-194

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Abstract

Introduction: To evaluate the efficacy of topical cyclosporin A 0.1% eye drops in management of moderate to severe perennial vernal keratoconjunctivitis.
Methods: Fourteen patients with moderate to severe perennial vernal keratoconjunctivitis, who were dependent on steroid eye drops for control of disease, were administered 0.1% cyclosporin A eye drops twice a day. Signs, symptoms and steroid score were calculated at start of study, and then at two monthly interval.
Results: Ten males and four females, between age of 3 – 17 years were enrolled in this study. Treatment with cyclosporin A 0.1% eye drops decreased the symptom, sign and steroid score at 12 months (p<0.0001, paired t test). Steroid sparing effect was seen in five patients at the end of study period.
Conclusions: Topical cyclosporin A 0.1% eye drops can be used as a steroid sparing agent in the management of perennial vernal keratoconjunctivitis.

Keywords: Cyclosporin A, Perennial vernal keratoconjunctivitis

How to cite : Dwivedi K, Singh A K, Hauhner V, Agasti M, Role of cyclosporin 0.1% in perennial vernal keratoconjunctivitis. Indian J Clin Exp Ophthalmol 2016;2(3):190-194

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