Indian Journal of Clinical and Experimental Ophthalmology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2395-1443
Online ISSN: 2395-1451
CODEN : IJCEKF
Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...Original Article
Author Details :
Volume : 10, Issue : 4, Year : 2024
Article Page : 746-753
https://doi.org/10.18231/j.ijceo.2024.130
Abstract
Background: Diabetes mellitus causes several ophthalmic complications including retinopathy, cataract, and damage to the anterior chamber of the eye including various layers of the cornea.
Aim: To compare endothelial cell loss after phacoemulsification surgery for cataracts among diabetics and non-diabetic patients.
Materials and Methods: A single-centre, hospital-based, prospective, comparative, 1:1 observational study enrolling participants a total of 200 participants were enrolled (100 diabetic and non-diabetic) and were followed up from the preoperative period to 3 months after surgery. The data pertaining to endothelial cell density, coefficient of variance, endothelial cell hexagonality and central corneal thickness were recorded using specular microscopy before, 1-, 7-, 30-, and 90 days after cataract surgery.
Results: There was a significant difference (p<0>10 years of diabetes and highest among patients with < 5> 10 years of diabetes was 65.7%, 62.5% and 57.5%, respectively.
Conclusion: In comparison to non-diabetic patients, there was a considerable loss of endothelial cell function among diabetic individuals following cataract surgery. Furthermore, a slower and poorer healing response was seen in patients with diabetes.
Keywords: Endothelial cell, Phacoemulsification, Endothelial cell hexagonality, Central corneal.
How to cite : Upadhyaya P, Raghuvanshi A S, Comparison of endothelial cell loss using specular microscopy in diabetic verses non-diabetic patients undergoing phacoemulsification surgery at an eye hospital in central India. Indian J Clin Exp Ophthalmol 2024;10(4):746-753
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