Indian Journal of Clinical and Experimental Ophthalmology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2395-1443
Online ISSN: 2395-1451
CODEN : IJCEKF
Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...Case Report
Author Details :
Volume : 10, Issue : 2, Year : 2024
Article Page : 391-394
https://doi.org/10.18231/j.ijceo.2024.069
Abstract
Background: Combined hamartoma of the retina and retinal pigment epithelium (CHR-RPE) represents a rare, benign congenital anomaly typically presenting as slightly elevated, variably pigmented lesions. This report details the surgical outcome and histopathological features of an epiretinal membrane associated with CHR-RPE.
Materials and Methods: A 29-year-old woman with a three-year history of gradual visual decline in her right eye underwent a comprehensive ophthalmologic examination, including spectral domain optical coherence tomography (SD-OCT), which revealed characteristic features of CHR-RPE and an overlying epiretinal membrane. She subsequently elected to undergo pars plana vitrectomy with membrane peeling.
Results: Intraoperative findings confirmed the presence of histological elements consistent with the internal limiting membrane, fibrillar collagen, vitreous, and cells positive for glial fibrillary acidic protein (GFAP), indicative of glial cells. Postoperatively, there was a noticeable improvement in the retinal architecture; however, visual acuity improvement was minimal. Histopathological analysis of the excised membrane provided insight into the lesion’s cellular composition.
Conclusion: This case underscores the complex nature of CHR-RPE associated with epiretinal membranes and the challenges in achieving significant visual acuity improvement despite successful surgical intervention. It highlights the importance of early detection and a personalized approach to management. Future research should focus on optimizing treatment strategies and improving understanding of the prognosis for similar cases.
Keywords: Epiretinal membrane, Combined hamartoma, Retina, Retinal pigment epithelium, Surgical outcome, Histopathological features.
How to cite : Jarallah O J A, Epiretinal membrane associated with combined hamartoma of retina pigment epithelium: Surgical outcome and histopathological features. Indian J Clin Exp Ophthalmol 2024;10(2):391-394
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