Print ISSN: 2395-1443
Online ISSN: 2395-1451
CODEN : IJCEKF
Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...Original Article
Author Details :
Volume : 10, Issue : 2, Year : 2024
Article Page : 368-372
https://doi.org/10.18231/j.ijceo.2024.065
Abstract
Background: Diabetic retinopathy and retinal vein occlusion are significant causes of vision loss in patients with diabetes. Emerging evidence suggests that vitamin D deficiency and elevated homocysteine levels may play a role in the pathogenesis of these conditions. This study investigates the serum levels of vitamin D and homocysteine in patients with diabetic retinopathy and retinal vein occlusion to elucidate potential associations.
Aim: Diabetic retinopathy (DR) is a sight threatening complications associated with diabetes mellitus. To find the correlation between vitamin D level and homocysteine plasma levels in patients of DR and Retinal Vein Occlusion patients.
Objective: Study the level of serum vitamin D and Homocysteine in patients with diabetic retinopathy as well as in retinal vein occlusions.
Materials and Methods: A case control type of study was conducted on 100 cases (70 diabetic retinopathy and 30 retinal vein occlusion) and age matched 100 control. Detailed relevant history and complete ocular examination was done . Serum vitamin D and homocysteine levels were noted.
Result: In our study, majority of the patients belonged to & > 60 years in the group of cases of diabetic retinopathy and most of the patients in the control group belonged to 50-60 years and & > 60 years of age group (40%). Mean age in the cases and controls was equal (58.4±8.4)
Majority of the patients in both cases (68.6%) and control (67.1%) group were males. Association was found to be statistically significant when chi square test (p = 0.03). The prevalence of hyper homocysteinenemia was also higher in DR group.
Conclusion: The prevalence of hyperhomocystinemia was more in cases of diabetic retinopathy compared to controls. The prevalence of vitamin D deficiency was more in cases of diabetic retinopathy compared to controls and the difference was significant.
Keywords: Diabetes mellitus, Diabetic retinopathy, Serum vitamin D, Serum Homocysteine, Retinal vein occlusion.
How to cite : Tadwalkar A, Sahay S, Menon P, Kumari P, Study of serum vitamin D and homocysteine levels in patients with diabetic retinopathy and retinal vein occlusion. Indian J Clin Exp Ophthalmol 2024;10(2):368-372
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