Indian Journal of Clinical and Experimental Ophthalmology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2395-1443
Online ISSN: 2395-1451
CODEN : IJCEKF
Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...Original Article
Author Details :
Volume : 10, Issue : 2, Year : 2024
Article Page : 332-337
https://doi.org/10.18231/j.ijceo.2024.059
Abstract
Background: Pseudoexfoliation syndrome (PEX) is the most common cause of secondary open angle glaucoma. It is a systemic disorder characterized by extracellular deposition of distinctive grey-white fibrillary amyloid like material. The material is found in the anterior segment of the eye, where it can be easily identified on ocular (slit- lamp) examination by ophthalmologists. This study was carried out to determine if an association does exist between ocular pseudoexfoliation and cardiovascular disease.
Materials and Methods: This was a cross-sectional case-control study carried out from March 2023 to June 2023 at a tertiary hospital. A total of 46 cases (patients with ocular pseudoexfoliation) and 46 controls (patients without ocular pseudoexfoliation) were randomly selected from Ophthalmology Outpatient Department. Ophthalmological examination was done which included visual acuity testing using standard Snellen’s Chart, anterior segment assessment by slit lamp examination, Goldmann Applanation Tonometry to check intraocular pressure (IOP) and dilated fundus examination by direct/indirect ophthalmoscopy. Blood pressure (BP) was assessed and Electrocardiogram (ECG) was performed for all the patients undergoing the study. 2D Echocardiogram (ECHO) was done if ECG was abnormal.
Results: Analysis of the study results showed a positive association between ocular pseudoexfoliation and hypertension (HTN) and abnormal ECG. Also, the condition appeared to be more prevalent among the males.
Conclusion: Since there is a positive association between pseudoexfoliation and cardiovascular diseases (CVD), ophthalmologists need to proactively investigate patients with PEX for cardiovascular abnormalities in form of HTN and abnormal ECG and refer them to physicians for appropriate management, if necessary.
Keywords: Ocular pseudoexfoliation, Cardiovascular disease, Hypertension, ECG.
How to cite : Ramalingam U, Annamalai R, James J M, Association between ocular pseudoexfoliation and cardiovascular disease status: An analysis in a multi-speciality Hospital. Indian J Clin Exp Ophthalmol 2024;10(2):332-337
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