Indian Journal of Clinical and Experimental Ophthalmology

Print ISSN: 2395-1443

Online ISSN: 2395-1451

CODEN : IJCEKF

Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...

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Original Article


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183- 188


Authors Details

Ram Kumar Jaiswal, Ram Yash Singh Yadav, Rajshree Pandey*


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Study of changes in choroidal thickness with severity of diabetic retinopathy and diabetic macular edema in type 2 diabetic patients


Original Article

Author Details : Ram Kumar Jaiswal, Ram Yash Singh Yadav, Rajshree Pandey*

Volume : 9, Issue : 2, Year : 2023

Article Page : 183-188

https://doi.org/10.18231/j.ijceo.2023.035



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Abstract

Introduction: Diabetic (DR) is one of the long-term complications of Diabetes. Chronic hyperglycemia cause abnormalities to both retina and choroid. Optical coherence tomography (OCT) is a non-invasive imaging modality, which plays a vital role in revealing the and development of retinal– diseases.

Materials and Methods: This prospective observational study included 128 eyes of 64 subjects diagnosed with type 2 diabetes and out of 128 eyes, 113 (88%) eyes were found to have DR. Collected data included age, gender, duration of diabetes, control, comprehensive ocular examination, photography, and CT measurement on OCT.

Results: Mean age in the study group was 53.71 ± 9.37 years (45–70 years). Out of 113 eyes, 19 (17%) eyes were diagnosed as mild NPDR, 21 (19%) eyes had moderate NPDR, 36 (31%) eyes had severe NPDR and 37 (33%) eyes had PDR. The average SFCT in MILD NPDR was 310 ± 14.70 at 95% CI (1.86), MODERATE NPDR was 316 ± 17.97 at 95% CI (2.70), SEVERE NPDR was 326.02 ± 14.05 at 95% CI (4.59) and PDR was 298.55 ± 18.75?m at 95% CI. (1.41). The presence of DME significantly affects average SFCT. It was observed that thickness tends to increase as the severity DR with DME progress.

Conclusions: The average SFCT was thicker in patients with increase in severity of DR, and then SFCT decreased in patients with PDR. As the severity of NPDR increased from mild to moderate to severe NPDR, there was increase in sub thickness. (p<0.05). PDR showed decrease in sub thickness in comparison to NPDR which is highly statistically significant. p=0.01 (p<0.05). The presence of DME significantly affects average SFCT (p<0.05). It was observed that thickness tends to increase as the severity DR with DME progress. Thus, thickness measurement can help in assessment of DR.


How to cite : Jaiswal R K, Yadav R Y S, Pandey R, Study of changes in choroidal thickness with severity of diabetic retinopathy and diabetic macular edema in type 2 diabetic patients. Indian J Clin Exp Ophthalmol 2023;9(2):183-188

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