Indian Journal of Clinical and Experimental Ophthalmology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2395-1443
Online ISSN: 2395-1451
CODEN : IJCEKF
Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...Original Article
Author Details :
Volume : 8, Issue : 4, Year : 2022
Article Page : 533-537
https://doi.org/10.18231/j.ijceo.2022.108
Abstract
Introduction: The retinal nerve fibre layer is a most crucial indicator of optic nerve damage in glaucoma as it advances visual field loss. Thickness of the RNFL can be measured using high resolution OCT. We conducted this study to evaluate the alterations in retinal nerve fibre layer thickness measured by SD- OCT in ametropes and to find various factors affecting RNFL thickness.
Aim: Study of retinal nerve fibre layer thickness (RNFL) by Optical Coherence Tomography (OCT) in ametropes in tertiary care hospital of central India.
Setting and Design: Hospital based prospective observational study included 300 eyes of 150 participants. Visiting ophthalmology outpatient department Gandhi medical college and fulfilling the inclusion and exclusion criteria.
Materials and Methods: Patients were divided into five groups of 60 eyes each on the basis of refractive status of eyes into emetropia, low hypermetropia, moderate hypermetropia, low mypopia and moderate mypopia. Subjects were subjected to OCT scan and RNFL thickness was measured. All groups were evaluated and observations were noted and results were analysed.
Statistical Analysis used: To find the association between degree of ametropia and RNFL thickness one way ANOVA test was used. Correlation between axial length and RNFL was assesed by pearson correlation coefficient. p value <0>
Result: RNFL thickness in different groups followed ISNT rule with inferior quadrant showing the greatest thickness followed by the superior, nasal and temporal quadrants. The average RNFL thickness in emmetropics, Low hyperopic, Moderate hyperopic, Low myopic, Moderate myopic was 111.90?m, 110.58 ?m, 114.59 ?m, 103.33 ?m, 93.33 ?m respectively, wheras average axial length was 23.85mm, 22.36mm, 21.33mm, 24.72mm, 25.63mm.
Conclusion: With the help of OCT, we can differentiate the changes in RNFL thickness in various refractive errors. So, the refractive status of the eye should be kept in mind before making any ocular diagnosis in which the RNFL is a diagnostic criteria.
Keywords: Spectral domain optical coherence tomography (SD-OCT), Retinal nerve fibre layer (RNFL) thickness, Refractive errors (RE).
How to cite : Gupta R, Dubey A, Singh M, Raichandani D, Kumar K, Som V, SD-OCT guided analysis of retinal nerve fibre layer in ammetropes in central India. Indian J Clin Exp Ophthalmol 2022;8(4):533-537
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