---

Ocular manifestations of Hutchinson-Gilford-Progeria syndrome: A rare presentation

---

Case Report

Author Details : Chandana Sultana, Sharah Rahman*, Sarwar Alam, Syeed Mehbub Ul Kadir, Abdul Muntakim Shahid, Rashed Alam, A S M Moinuddin

Volume : 8, Issue : 2, Year : 2022

Article Page : 298-302

https://doi.org/10.18231/j.ijceo.2022.060

Suggest article by email

Get Permission

---

Abstract

The Hutchinson-Gilford Progeria (HGP) syndrome is an exceptionally rare genetic condition characterized by premature and accelerated aging in children. It is demonstrated by developmental delay along with progressive degenerative changes of the integumentary, musculoskeletal, cardiac, and vascular systems. In this case report, we describe the ocular manifestations of Hutchinson-Gilford Progeria (HGP) syndrome of a 20-year-old Bangladeshi boy. The patient had the classic triad of prominent eyes, loss of eyebrows or madarosis and lagophthalmos, which are the most common ocular manifestations.He also developed dry eye, keratinized ocular surface, Meibomian gland dysfunction, vascularized cornea, symblepharon, corneal opacification, and cataract. He had several systemic manifeastations that included senile facies, prominent scalp veins, generalized alopecia with plucked bird appearance, and sclerodermatous changes.
 

Keywords: Hutchinson­gilford, Progeria, Premature, Corneal keratinization, Loss of eyebrow

How to cite : Sultana C, Rahman S, Alam S, Kadir S M U, Shahid A M, Alam R, Moinuddin A S M, Ocular manifestations of Hutchinson-Gilford-Progeria syndrome: A rare presentation. Indian J Clin Exp Ophthalmol 2022;8(2):298-302

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.