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Dry eye disease associated with Primary Sjogren syndrome: An update

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Review Article

Author Details : Rajendra P Maurya*, Vibha Singh, Ashish Gupta, Virendra P Singh, Amit Kumar, Archana Yadav, Shivangi Singh

Volume : 7, Issue : 2, Year : 2021

Article Page : 259-269

https://doi.org/10.18231/j.ijceo.2021.055

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Abstract

Primary Sjögren’s syndrome (pSS) is a chronic, multisystem autoimmune disorder, characterized by mononuclear infiltration of exocrine glands and other organs, resulting in dry eye, dry mouth and extra-glandular systemic findings. Primary Sjögren syndrome is of particular interest to ophthalmologists as it constitutes an important differential diagnosis in conditions with dry eye disease. The ocular tests are of great importance for diagnosis and monitoring of primary sjogren’s syndrome. Also a better understanding of immunological mechanisms and molecular pathways have resulted in discovery of new therapeutics for local and systemic treatment. This article illustrates an update regarding pathogenesis, diagnosis, investigative procedures and treatment options for dry eye related to Sjogren’s syndrome.

Keywords: Dry eye disease,Sjogren syndrome.

How to cite : Maurya R P, Singh V, Gupta A, Singh V P, Kumar A, Yadav A, Singh S, Dry eye disease associated with Primary Sjogren syndrome: An update. Indian J Clin Exp Ophthalmol 2021;7(2):259-269

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