Indian Journal of Clinical and Experimental Ophthalmology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2395-1443
Online ISSN: 2395-1451
CODEN : IJCEKF
Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...Original Article
Author Details :
Volume : 5, Issue : 4, Year : 2019
Article Page : 461-465
https://doi.org/10.18231/j.ijceo.2019.110
Abstract
Objective: To study the therapeutic effects of 2% rebamipide ophthalmic suspension in dry eye disease.
Materials and Methods: It was Prospective study of 80 patients diagnosed with dry eye syndrome from
Jun 2016 to April 2017. After complete ophthalmic examination all were treated with 2% rebamipide
suspension. Dry eye-related Symptom Score, anterior segment examination with slit lamp, Tear Film
Break-Up Time, Fluorescein Ocular Surface Staining Score(FOS) & Schirmer test were used to collect
data from patients at baseline & at 2, 4, 8 & 12 week visits.
Results: Mean dry eye-related symptom score showed a significant improvement from baseline at 2, 4,
8 & 12 weeks (9.80, 7.20, 7.40 & 7.83 points). Median FOS also showed significant improvement from
baseline (3.0 points) at 2, 4, 8 & 12 weeks (2.0, 2.0, 1.0 & 1.0 points respectively). TBUT & Schirmer test
values also improved but were not significant after treatment.
Conclusion: 2% rebamipide ophthalmic suspension is an effective in treating dry eye. It helps in improving
both ocular & tear film stability.
Keywords: Dry eye syndrome, Tear film, Rebamipide, Mucin Secretion.
How to cite : Prakash D N, Sajjan S, Satish K, Raghavendra R, Kayoom M A, Role of 2% rebamipide ophthalmic suspension in the management of dry eye disease. Indian J Clin Exp Ophthalmol 2019;5(4):461-465
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