Indian Journal of Clinical and Experimental Ophthalmology

Print ISSN: 2395-1443

Online ISSN: 2395-1451

CODEN : IJCEKF

Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...

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Genetic and Environmental Interactions in Myopia

  • Aksha Shetty,*  
  • Anasuya Ganguly

Abstract

Abstract Clinical relevance: An environment-genetic score is a measure that combines information about a person's genetic predisposition and environmental factors that may contribute to the development of a certain condition. This score can help optometrists and other eye care professionals make more informed and personalized decisions regarding the management and treatment of myopia. Background: Interaction between lifestyle and family history of myopia plays an important role in the development of myopia and myopia progression. It is important to understand this interaction to develop holistic treatment approaches. Methods: A cross-sectional study was conducted in the outpatient department of ophthalmology in the state of Goa, India. Children aged between 7 and 15 years were included. Children with visual acuity of less than 0.1 logMAR later underwent objective and subjective refraction. A prevalidated questionnaire was used to assess the environmental impact on myopia. Parental myopia was recorded. An Environmental Genetic Index (EGI) can be created to evaluate the risk of myopia in a given population. The difference between the prevalence of myopia in these families is defined as EGI. Results: A total of 152 children were evaluated, out of which 64 (42.10 %) were females. This study included 75 myopes (49.34 %) and 77 emmetropes (50.66 %). The prevalence of myopia in the myopic family was 85.71%, in the one-sided-myopic family was 60%, and in the non-myopic family was 45%. The environmental genetic index was 0.4071, suggesting that genetic factors may play a 40.71% role in the formation of myopia and environmental factors may play a 59.29 % role in the development of myopia. Conclusion: In the studied population genetic factors may played a 40.71% role in the formation of myopia. There was no difference seen in outdoor time and screen time between myopes and emmetropes.


Keywords

Myopia,Environment ,EGI, Genetic, Parental Myopia